Immunology Congress 2018

Call for Papers

Sessions & Tracks

#Track 1: Immunogenomics

Immunogenomics originally was framed by research supporting the hypothesis that cancer mutations generated novel peptides seen as ‘‘non-self’’ by the immune system. ‘Neoantigens’ has been facilitated by the combination of specialized computational analyses, new sequencing technologies, and HLA binding predictions that evaluate somatic alterations in a cancer genome and interpret their ability to produce an immune-stimulatory peptide. The resulting information can characterize a tumor’s Neoantigens load, its cadre of infiltrating immune cell types, the T or B cell receptor repertoire, and direct the design of a personalized therapeutic.

#Track 2:Veterinary Immunology & Immunopathology

Veterinary immunology is the study of all features of the immune system in animals. It is a division of biomedical science and associated to zoology and veterinary sciences. It is engrossed in how the immune system works, how vaccines thwart disease and why vaccines occasionally do not work and cause antagonistic responses. Every living creature is constantly presented with substances that are not fit for their upbringing. Most living beings secure themselves against such substances in more than one way with physical barriers, for example, or with chemicals that repulse or slaughter invaders. Creatures with spines, called vertebrates, have these sorts of general defensive instruments; however, they additionally have a more progressed defensive framework called the immune system. The invulnerable framework is a perplexing system of organs containing cells that perceive outside substances in the body and devastate them. It secures vertebrates against pathogens, or irresistible specialists, for example, infections, microscopic organisms, growths, and different parasites. The human immune system is the most complex. Although there are numerous possibly unsafe pathogens, no pathogen can invade or attack all organisms because a pathogen's ability to cause harm requires a susceptible victim, and not all creatures are powerless to similar pathogens. For example, the infection that causes AIDS in people does not contaminate creatures, for example, dogs, cats, and mice. Correspondingly, people are not defenseless to the infections that cause canine distemper, cat leukemia, and mousepox.

#Track 3: Vaccines & Immunotherapy

The vaccine is a biological preparation that enhances resistance to specific infection. It contains particular operators that look like an illness bringing about the microorganism as well as animates body's safe framework to perceive the outside specialists. A vaccine is dead or inactivated life forms or refined items gotten from them. Entire creature antibodies cleaned macromolecules as vaccines, recombinant antibodies, DNA antibodies. The insusceptible framework perceives vaccine specialists as remote, devastates them, and "recollects that" them.

Immunotherapy is a standout amongst the most energizing ranges of new disclosures and medicines for various sorts of a tumor. Seeing how the insusceptible framework functions are opening the ways to grow new medicines that are changing the way we consider and treat growth. The vast majority accepting immunotherapies are dealt with in particular malignancy focuses and a large portion of them are selected in clinical trials. This may change as more trials are finished and more medications are affirmed by the Food and Drug Administration (FDA) to treat various types of malignancy.

#Track 4:Immunotoxicology & Molecular Biomarkers

Immunotoxicology is the investigation of immune dysfunction resulting from exposure of an organism to a xenobiotic. Immunotoxicology is moderately new interdisciplinary logical field concentrated on recognizable proof and investigation of the compound and, in a more extensive sense, additionally physical and organic elements of nature which can bring about undesirable and normally accidental immunomodulation. The immune dysfunction may take the form of immunosuppression, sensitivity, autoimmunity, and incendiary based illnesses. Insusceptible System assumes a basic part in host imperviousness to sickness and additionally in typical homeostasis of a living being; recognizable proof of immunotoxic hazard is huge in the assurance of human, creature and wildlife health. In addition, immunotoxicology likewise researches the properties of new immunotherapeutic pharmacological items arranged by means of recombinant DNA methods (interleukins, interferons, development variables, hostile to irritation drugs, neuroendocrine hormones, neuropeptides with respect to their immunotoxic potential and security of their utilization.

###pbiomarker is a trademark that can be unbiasedly measured as a marker of typical organic procedures, pathogenic procedures or a pharmacological reaction to a restorative mediation. These are utilized for some reasons including malady conclusion and guess, forecast and appraisal of treatment reaction. Biomarkers can be trademark natural properties or particles that can be recognized and measured in parts of the body like the blood or tissue. They may show either ordinary or infected procedure in the body. Biomarkers can be particular cells, particles, or genes, gene items, catalysts, or hormones

#Track 5:Immunoresearch & Immunotechnology

Immunology is worried about the utilization of immunological responses for the determination, avoidance, and treatment of various infections. It is firmly identified with therapeutic and veterinary microbiology, the study of disease transmission, physiology and Pathophysiology, organic chemistry, and endocrinology. Viral Immunology and the immunology of parasitic infections are autonomous branches of commonsense immunology. Immunology concentrates the antigenic creation of microorganisms, attributes of the safety procedures in different sorts of contaminations, and nonspecific types of Imperviousness to the causative operators of irresistible infections. Investigation of the immunological procedures and the immunological reproduction of the living being created by Non-infectious Antigens of the exogenous and endogenous starting point and the advancement of strategies for controlling unfavorably susceptible sicknesses are winding up noticeably progressively imperative. Different branches of clinical immunology are likewise growing seriously. These incorporate radiation immunology, which concentrates the disturbance of immunological reactivity by illumination, and Immunohematology, which researches the antigenic piece of platelets and the causes and instrument of advancement of immunological harm to the circulatory framework. Immunology is creating techniques for Immunoprophylaxis, Immunotherapy, and Immunodiagnostics.

Immunologic Research speaks to an interesting medium for the introduction, translation, and elucidation of complex logical information. Data is displayed as interpretive combination surveys, unique research articles, symposia, publications, and hypothetical expositions. The extent of scope stretches out to cell immunology, immunogenetics, sub-atomic and auxiliary immunology, immunoregulation and autoimmunity, immunopathology, tumor immunology, have safeguard and microbial resistance, including viral immunology, immunohematology, mucosal invulnerability, supplement, transplantation immunology, clinical immunology, neuroimmunology, immunoendocrinology, immunotoxicology, translational immunology, and history of immunology.

#Track 6: Immunological Clinical Practices &Trials

Immunological Clinical trial is a unique research program designed to cultivate a collaborative environment that allows basic and translational immunologists to work side-by-side with clinicians. Clinical trial & Practices are always designed to gain some knowledge about something not yet well-known or proven. A person may volunteer to participate in a clinical study. A physician may recommend a patient to consider volunteering for specific study participation, as part of the patient therapeutic treatment options.  Clinical trials are highly regulated and are conducted following strict scientific standards in order to protect patients and to produce meaningful results.

The clinical trial allows accelerating the bench-to-bedside transition of innovative immunotherapies, with much attention given to critical diseases which are known to relapse or is refractive to conventional treatments currently available. Many of the novel immunotherapy approaches, which originated from basic science research by the clinical trial and practices, are now being explored as new treatment modalities in patients, with a significant number advancing through clinical trials towards FDA approval.

#Track 7: Pediatrics Immunology

Pediatric Immunology.  Child’s immune system battles against infections. On the off chance that the child has hypersensitivities, their resistant framework wrongly responds to things that are normally innocuous. Pet dander, dust, tidy, form spores, bug stings, nourishment, and solutions are cases of such things. This response may make their body react to medical issues, for example, asthma, roughage fever, hives, dermatitis (a rash), or an exceptionally extreme and unordinary response called anaphylaxis. Once in a while, if your child’s invulnerable framework is not working right, he may experience the ill effects of successive, serious, or potentially unprecedented diseases. Cases of such contaminations are sinusitis (aggravation of at least one of the sinuses), pneumonia (disease of the lung), thrush (a growth contamination in the mouth), and abscesses (accumulations of discharge encompassed by kindled tissue) that continue returning.

#Track 8: Immunosenescence

###plower-affinity antibodies, a failure to generate long-lasting immunity to vaccination and a loss of delayed-type hypersensitivity to antigens previously encountered in life. Bacterial and viral diseases such as tuberculosis and herpes zoster (shingles), respectively, are found much more frequently in the elderly compared to young adults. Septicemia (infectious microbes in the bloodstream) is also more common in the elderly. Pneumonia is more prevalent and more often fatal and other viral and bacterial infections are more common in older people leading to an increase in morbidity and mortality. This decline in immune competence is not solely a result of a defective immune system, as it is also a result of changes in the endocrine and nervous systems, as well as nutritional and other factors including the general state of health of the older individual.

Malignancies are seen much more frequently in older people and while many of these may be related to inappropriate DNA translational events, a defective immune system may also be responsible since there is an association between immune deficiency and increased malignancy. Defects in all compartments of the immune system have been reported in the elderly. While studies are often contradictory, reliable data indicate that defects develop in T and B cell immunity as well as in the phagocytic component of immunity. Increased NK cell numbers and decreased γδ T cell function is also a feature of aging. IL-6 and IL-10 production by monocytes is increased with aging as well as the pro-inflammatory cytokines IL-1β and TNFα. MHC molecules are expressed at a lower density on a variety of cells and fewer T cells expressing CD28, important for T cell signaling, are found in the elderly. Antibody responses are usually of lower affinity and autoantibodies are found much more frequently. Hemopoiesis is impaired with fewer progenitor cells produced. Thymic involution is well established in the elderly with fewer T cells entering the vascular pool and hence secondary lymphoid organs. AICD and apoptosis are increased. Age-related changes in hormonal and neurotransmitter function may also have an impact on immune function and may determine morbidity, mortality, and longevity.

 #Track 9: Cancer & Tumor Immunology

The immune system is the body's initial line of barrier against most illnesses and irresistible intruders. Seeing how the immune system functions—or does not work—against growth is an essential concentration of the Cancer Immunology Program. Specialists are decoding the fundamental science of safe reactions with the objective of growing new safe treatment approaches and enhancing existing ones. The Huge concentrate is on consolidated methodologies that expand upon disclosures in malignancy hereditary qualities (changes to DNA), epigenetics (concoction modifications to the earth of DNA) and immunology. Late revelations utilize new discoveries about how the immune system capacities to make collaboration and enhance the viability of surgery, disease antibodies, medicate treatments and radiation treatment. Accuracy, or customized, medication is utilized to control the best invulnerable ways to deal with the correct patients, and this energizing work is prompting dependable reactions in numerous growths. Eventually, scientists hope to unravel why insusceptible treatments work for a few patients and not others, enrolling the body's own particular safeguards against for all intents and purposes each sort of growth.

#Track 10: Allergies & Hypersensitivity

Allergies represent TYPE I responses as per the Gell and Coombs grouping. Most are brought about by IgE ANTIBODIES which are fit for the official to Fc-receptors for IgE on tissue MAST CELLS. Cross-connecting of these layers bound IgE's by particular antigen brings about pole cell DEGRANULATION; this procedure discharges HISTAMINE and an assortment of other effector molecules, which thus brings about the bunch side effects of sensitivity. (rash, feed fever, asthma and so on.) Passive cutaneous hypersensitivity (PCA) in the guinea pig and the Prausnitz-Küstner (P-K) skin response in people give models to understanding the basic component of unfavorably susceptible responses. Administration of sensitivities starts with allergen shirking and incorporates the utilization of an assortment of medications and allergen-particular DESENSITIZATION.

#Track 11: Clinical Immunology: Current & Future Trends

Clinical Immunology has developed in the course of recent decades from a transcendent research center base to a joined clinical and lab claim to fame. The clinical work of Immunologists is to a great extent out-patient based and includes essential immunodeficiency, hypersensitivity, immune system rheumatic ailment and systemic vasculitis (mutually with Rheumatologists), joint pediatric centers for kids with immunodeficiency and sensitivity and immunoglobulin imbuement facilities for patients with immunizer lack. On the research center front, Consultant Immunologists are in charge of coordinating demonstrative immunology benefits and play out an extensive variety of obligations including clinical contact, elucidation and approval of results, quality confirmation and test improvement.

#Track 12 : Lymph-proliferative Disorders

Lymphoproliferative disorders are an arrangement of scatters described by the abnormal proliferation of lymphocytes into a monoclonal lymphocytosis. The two noteworthy sorts of lymphocytes are B cells and T cells, which are gotten from pluripotent hematopoietic foundational microorganisms in the bone marrow. People who have some kind of brokenness with their immune system are powerless to build up a lymphoproliferative disorder since when any of the various control purposes of the resistant framework end up noticeably useless, immunodeficiency or deregulation of lymphocytes will probably happen. There are a few acquired quality transformations that have been distinguished to bring about lymphoproliferative disorder; in any case, there are additionally gained and iatrogenic causes.

#Track 13:Immunodermatology

Immunodermatology thinks about skin as an organ of insusceptibility in wellbeing and malady. A few territories have extraordinary consideration, for example, photograph immunology (impacts of UV light on skin guard), incendiary illnesses, for example, Hidradenitis suppurativa, unfavorably susceptible contact dermatitis and atopic dermatitis, probably immune system skin ailments, for example, vitiligo and psoriasis, lastly the immunology of microbial skin ailments, for example, retrovirus contaminations and sickness. New treatments being developed for the immunomodulation of basic immunological skin sicknesses incorporate biologicals gone for killing TNF-alfa and chemokine receptor inhibitors.

#Track 14: Immunohematology

Immunohematology is the study of the immunology and genetics of blood cell antigens, blood groups and specific blood proteins(such as complement) and antibodies esp. important in blood banking and transfusion medicine.

Immunohematology is more commonly known as "blood banking" or “blood biology”.

This is the field of laboratory medicine dealing with preparing blood components and blood for transfusion as well a the selection of compatible and appropriate components for transfusion. Individuals may become immunized to red blood cells due to previous exposure to red blood cells(RBCs) of other people, most commonly through transfusion or pregnancy. Our children basically receive immunizations which leads to form antibodies against the immunizing material, such as tetanus. If they are again exposed to the organism which causes tetanus, the antibodies will destroy them before they can cause infection. In a similar way, red blood cells have specific structures on their surface called antigens. If an individual is pregnant with a fetus or transfused with blood that possesses structures which the recipient or mother does not have, this may induce the individual to form antibodies. These antibodies may then destroy red blood cells(RBCs) which possess the antigen if additional sessions of transfusions are needed. That is why all blood banks will "screen" potential blood recipients for unexpected antibodies and they will then select blood which lacks the offending antigen. The formation of these antibodies is an unusual occurrence, occurring in approximately 0.1-3

#Track 15: Humoral & Cellular Immunology

Our immune system distinguishes two categories of foreign substances. One category consists of antigens (foreign substances) that are freely circulating in the body. These include molecules, viruses, and foreign cells. The Second Category consists of self-cells that display aberrant MHC(Major Histocompatibility Complex) proteins. These aberrant MHC proteins can originate from antigens that have been engulfed and broken down (exogenous antigens) or from tumor cells and virus‐infected that are actively synthesizing foreign proteins (endogenous antigens).

Depending on the kind of foreign invasion, two different immune responses occur:

The Humoral Immunology or Humoral response (or antibody‐mediated response) involves B cells that pathogens or recognize antigens that are circulating in the lymph or blood (“humor” is a medieval term for body fluid). In this, the antigens bind to B cells which lead to Interleukins or helper T cells stimulate B cells.

The Cellular Immunology or Cell‐mediated response involves mostly T-cells and responds to any cell that displays aberrant MHC markers, including cells invaded by pathogens, tumor cells, or transplanted cells. Self-cells or Antigen Presenting Cells (APCs) displaying foreign antigens bind to T cells.

#Track 16: Neuroimmunology

The investigation of the connection between our central nervous system (the brain and spinal string) and our immune system. Neuroimmunology adds to the advancement of new pharmacological medications for a few neurological conditions. The immune system and the sensory system keep up broad correspondence, including "hardwiring" of thoughtful and parasympathetic nerves to lymphoid organs. Neurotransmitters, for example, acetylcholine, norepinephrine, vasoactive intestinal peptide, substance P, and histamine adjust the insusceptible action. Neuroendocrine hormones, for example, corticotrophin-discharging element, leptin, and alpha-melanocyte empowering hormone manage cytokine adjust. The immune system adjusts brain action, including body temperature, rest and bolstering conducts. Particles, for example, the significant histocompatibility complex not just direct T cells to immunogenic molecules held in its separated additionally regulate improvement of neuronal associations. Neurobiologists and immunologists are investigating normal thoughts like the neurotransmitter to comprehend properties.

#Track 17: Mucosal Immunology

The mucosal surfaces of the body have a higher danger of contamination because of their cooperative energy with the outside condition. Mucosal immunology raises those parts of the resistant framework that shield the body from contamination. It gives three main functions secures the mucous film against disease, keeping the take-up of antigens, microorganisms, and other outside materials, and directing the creature's insusceptible reaction to that material. The mucosal insusceptible framework is contained mechanical (bodily fluid), concoction and cell elements.

#Track 18: Autoimmune & Inflammatory Diseases

The immune system has the capacity to mount an immune response to virtually all molecules and/or cells. Although the capacity to respond to self-antigen is present in all of us, in most instances such responses result in tolerance, indicating that mechanisms must exist to prevent or subdue autoimmune responses. Moreover, auto-reactive T and B cells, as well as autoantibodies, are found in people who do not have autoimmune diseases, demonstrating that immunological auto-reactivity alone is not sufficient for the development of the disease. The mechanisms currently thought to prevent/dampen autoimmune responses include inactivation or deletion of autoreactive B and T cells, active suppression by cells or cytokines, idiotype or anti-idiotype interactions, and the immunosuppressive adrenal hormones, the glucocorticoids. When dampening mechanisms fail or are overridden, a response directed against self-antigen can occur, resulting in autoimmune diseases that range from those which are organ-specific (diabetes and thyroiditis) to those which are systemic (non-organ specific) such as systemic lupus erythematosus and rheumatoid arthritis.

#Track 19: Reproductive & Behavioral Immunology

Reproductive immunology refers to a field of medicine that studies interactions (or the absence of them) between the immune system and components related to the reproductive system, such as maternal immune tolerance towards the fetus, or immunological interactions across the blood-testis barrier. The immune system refers to all parts of the body that work to defend it against harmful enemies. In people with immunological fertility problems, their body identifies the part of reproductive function as an enemy and sends Natural Killer (NK) cells to attack. A healthy immune response would only identify an enemy correctly and attack only foreign invaders such as a virus, parasite, bacteria; etc.The concept of reproductive immunology is not widely accepted by all physicians. Those patients who have had repeated miscarriages and multiple failed IVF's find themselves exploring its possibilities as the reason. With an increased amount of success in treating any potential immunological factors, the idea of reproductive immunology can no longer be overlooked. The failure to conceive is often due to immunologic problems that can lead to very early rejection of the embryo, often before the pregnancy can be detected by even the most sensitive tests. Women can often produce perfectly healthy embryos that are lost through repeated "mini miscarriages." This most commonly occurs in women who have conditions such as endometriosis, an under-active thyroid gland or in cases of so-called "unexplained infertility." It has been estimated that an immune factor may be involved in up to 20% of couples with otherwise unexplained infertility. These are all conditions where abnormalities of the woman’s immune system may play an important role.

#Track 20: Microbial, Parasitic, Viral and Fungal immunology

Microbial immunology is the investigation of the molecular mechanisms utilized by microorganisms to bring about sickness in people and creatures. Bacterial, protozoan, parasitic and viral pathogens have built up a wide assortment of devices to build up themselves in the host and pick up supplements, which additionally cause impedance and malady. To comprehend the mind-boggling forms utilized by microbial pathogens, microbiologists and immunologists utilize every one of the devices of present-day sub-atomic science, hereditary qualities, harmfulness elements, tranquilize collaborations, organic chemistry, and biophysics. Seeing how microorganisms cause ailment is regularly the initial move toward the improvement of new antibodies and therapeutics .

#Track 21: Nutritional Immunology

Nutrition is critical to immune defense and resistance to pathogens, with consequences that affect the health, welfare, and reproductive success of individual organisms, and also has profound ecological and evolutionary implications. In humans, under-nutrition or under-nourished, notably of protein, is a major contributor to mortality and morbidity due to infectious diseases, particularly in the developing world. Likewise, over-nutrition and its associated metabolic disorders may impair immune function, increase susceptibility to infectious disease, and disrupt the relationship with symbiotic and commensal microbiota.

#Track 22: Eco-Immunology: Evolutive Aspects & Future Perspectives

Eco-immunology is an explicit example of how fruitful integrative & innovative approaches to biology can be. Since its emergence, Eco -immunology has sparked constructive debate on a wide range of topics, from the molecular & cellular mechanics of immune responses to the role of immunity in shaping the evolution of life histories. To complement the symposium Methods and Mechanisms in Eco-immunology and commemorate the inception of Disease Ecology and the Division of Eco-immunology within the Society for Integrative and Comparative Biology, we appraise the origins of Eco-immunology, with a focus on its continuing and valuable integration with disease ecology. The greatest contribution of Eco-immunology to wider biology has been the establishment of immunity as an integral part of organismal biology, one that may be regulated to maximize fitness in the context of costs, constraints, and complex interactions. As we discuss historical impediments and ongoing progress in Eco-immunology, in particular, the thorny issue of what Eco-immunologists should, should not, or cannot measure, and what novel contributions Eco-immunologists have made to the understanding of host-parasite interactions. Finally, we highlight & focus some areas to which Eco-immunology are likely to contribute in the near future.

#Track 23: Transplantation Immunology

Organ transplantation is the moving of an organ from one body to another or from a donor site to another location on the patient's own body, for the purpose of replacing the recipient's damaged or absent organ. Transplantation immunology is the sequence of immunological reactions that occur after the transplant. A major limitation to the success of transplantation is the immune response of the recipient to the donor tissue. A major barrier to transplantation is the process of rejection, in which the recipient's immune system recognizes the graft as being foreign and attacks it. During fetal life, within the thymus, a very important process called thymic education occurs. Immune cells that react with “self” antigens are killed by a process called apoptosis. The removal of these self-reactive cells, a process called negative selection, results in tolerance to our own proteins, ie, self-tolerance, and prevents autoimmune reactions.

 #Track 24: Computational Immunology

Computational Immunology and Immunological Bioinformatics are firm and rapidly developing examination fields. Though the previous expects to create numerical and additionally computational strategies to concentrate the progression of the cell and atomic substances amid the resistant reaction, the last concentrates on proposing techniques to examine enormous Genomic & proteomic immunological-related datasets and foresee new information for the most part by measurable derivation and machine learning calculations. The overabundance of information delivered by high-throughput instrumentation, remarkably genomics, Transcriptomics, Epigenetics, and Proteomics techniques, requires computational apparatuses for securing, stockpiling, and investigation of immunological information. The misuse of such an enormous measure of immunological information, for the most part, requires its change into computational issues, their answer utilizing scientific and computational methodologies, and after that, the interpretation of the got comes about into immunologically important translations.