The emergence and spread of antimicrobial resistance (AMR) has far reaching consequences for medical procedures and treatments, with many common drugs and interventions potentially rendered ineffective. In addition, the use of insecticides to control vectors populations remains a key measure for public health. Following years of intensive usage, the emergence of resistance jeopardizes the success of these control strategies worldwide. The 4th edition of the Institut Pasteur International Network Symposium will be focused on these major issues. This event is a unique opportunity for scientists worldwide to showcase their research on any topic related to microbes or vectors resistance.