6th International Conference on Computational Science and Engineering (CSE 2018) focuses on Complex systems, information and computation using mathematics and engineering techniques. This conference will act as a major forum for the presentation of innovative ideas, approaches, developments, and research projects in the area of Computation theory and applications. It will also serve to facilitate the exchange of information between researchers and industry professionals to discuss the latest issues and advancement in the area of advanced Computation and its applications will be covered during the conference.