The meeting will feature a unique combination of brief research reports, oral presentations, keynote lectures, open discussion, brief didactic methods lectures, a poster session, and a webcast. These presentations will be peer-reviewed and will focus on the core controversies in Alzheimer’s disease biology and biomarker research. The aim is to continue the tradition of the first 13 HAI meetings, bringing together a cross-disciplinary mass of panelists and presenters who will provide perspectives from neuropathology, neurochemistry, psychology, neurology, molecular imaging, clinical trials and biomarker research.