The conference BIMac 2019: “Computational approach to polymers in biological and soft matter” is a follow-up of the longstanding series of Bratislava conferences organized by the Polymer Institute, Slovak Academy of Sciences dating back to 1968. The meeting will be focused on the computational modeling of biological and soft matter with large variety of applications to polymer physics, biochemistry, biophysics, molecular biology and potentially to biotechnology, nanotechnology, or biomedicine.