The focus of the ICCB 2019 conference will be to bring together the latest and most relevant topics in the field of Computational Bioengineering. It will include computational methods for cardiovascular disease prediction with emphasis on biomechanics, biomedical decision support system, data mining, personalized diagnostics, bio-signal processing, protein structure prediction, biomedical image processing, analysis and visualization, high performance computing and nanomedicine. Authors will present with advanced research support tools for disease characterization, and the discovery of new knowledge; associations among heterogeneous data, that can improve the predictive power of the patient-model.