Inflammation

The 1st Immunology & Inflammation (I & I) Conference aims to serve as an international and interactive platform for exchange of ideas and scientific discussion on the latest ground-breaking discoveries in the field. The program comprises four sessions covering the key new developments, their impact on Life Science, and implications for modern medicine. We warmly invite you to join us for this 1st I & I Conference and look forward to your participation. Sincerely yours, The organizing committee: Michela Di Virgilio, Klaus Rajewsky, Helmut Kettenmann and Hans-Reimer Rodewald.

This conference is the second international meeting on DUBs and is unique in its focus on this class of enzymes. It will bring together researchers in this exciting field of research to discuss molecular mechanisms, cellular functions and physiological roles of DUBs. The recent development of highly specific inhibitors has led to a lot of interest in exploring these enzymes as therapeutic drug targets in a variety of disease settings ranging from infection and inflammation to cancer and neurodegeneration. Emerging new concepts in DUB regulation and translation will be a particular focus of this meeting.

This meeting focuses on the biology and signalling of the class I isoforms of PI3K, and the drugs that have been generated to interfere with their function in disease. After some challenging years in PI3K pathway drug development, good progress has recently been made, with 3 PI3K inhibitors now approved for oncology and several others in the registration pipeline. Basic science investigations continue to provide new insight into the clinical observations.